L glutamine for sickle cell disease: more than reducing redox Annals of Hematology Springer Nature Link In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Storage lesion: History and perspectives Alterations in red blood cells during condition of oxidative stress. Download Scientific Diagram Hemolytic Anemias Part 4: G6PD Deficiency; Pathophysiology,Morphology, clinical features Red & White Blood Cells Basicmedical Key